Gender Medicine Gap Blog

Clear, evidence-based health articles exploring how gender shapes diagnosis, treatment, and care.

Showing 25 to 31 of 31 articles

ICH E21: What Pregnant and Breastfeeding Patients and Clinicians Can Reasonably Expect

Overview Regulators and experts are increasingly arguing that pregnant and breastfeeding people should be considered for inclusion in clinical research rather t...

May 8, 2026
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From Mechanism to Label: Why Sex‑Specific Dosing Decisions Are Still Rare — and What the New FDA Draft Means

Why a biological difference doesn’t always become a dosing recommendation There is growing scientific evidence that biological sex can alter drug exposure, immu...

May 6, 2026
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Why Missing Sex and Gender Data Is the Hidden Weakness in Clinical AI — And What Clinicians Can Do

Summary Across medical imaging, algorithmic decision support, and even large language models, recent studies show that clinical AI can learn and act on sex- and...

May 6, 2026
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When reference ranges and clinical cutoffs diverge: sex, gender and the practical limits of diagnostic thresholds

Why the gap between reference intervals and clinical cutoffs matters Laboratory reference intervals and device cutoffs are often presented as neutral numbers, b...

May 6, 2026
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Within‑woman hormonal changes: an underrecognized source of variability in drugs and diagnostics

Why timing inside a woman's body matters for medicine Research and regulation increasingly recognize that sex matters in medicine, but most attention compares m...

May 4, 2026
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How Regulatory Shifts and Pharmacovigilance Reform Can Improve Detection of Sex-Specific Drug Safety Signals

Why the signal matters now Over the past two years regulators and global health bodies have moved from urging sex‑aware research to spelling out concrete expect...

May 4, 2026
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What the recent push for sex‑aware research means for patients and clinicians

Why the topic matters now Federal agencies, journals, and clinical investigators are increasingly asking that sex be treated as a key biological variable in res...

May 4, 2026
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