Gender Medicine Gap Blog

Can Blood Thinners Make Periods Heavier? What the Evidence Says

Anticoagulants can be associated with heavier menstrual bleeding, but research on drug differences and treatments is limited. Learn what to discuss with a clinician and when bleeding needs urgent assessment.

The Dosage Gap in Neuromodulation: How Female Anatomy Challenges Standard TMS Protocols

Women’s shorter scalp-to-cortex distances result in significantly stronger electrical fields during standard TMS sessions. New FDA guidance and 2024 efficacy data reveal distinct sex-response patterns across stimulation protocols, highlighting urgent dosing gaps.

The Silent Fragmentation: Addressing Diagnostic Disparities in Female Sleep Apnea

Up to 75% of women with obstructive sleep apnea remain undiagnosed due to male-centric diagnostic standards. New research highlights the need for revised criteria to address female-specific symptoms like fatigue and sleep fragmentation.

Rising Rates, Silent Risks: Navigating the Congenital Syphilis Crisis in Prenatal Care

With congenital syphilis cases surpassing 4,000 in 2024, new ACOG guidelines recommend triple screening. We examine rising risks in rural and white demographics and persistent treatment gaps.

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The Hidden Hepatic Hazard: Why Women Face Higher Risks of Drug-Induced Liver Injury

Women face a significantly higher incidence and severity of idiosyncratic drug-induced liver injury due to metabolic enzyme variability and historical trial exclusion. This article examines the physiological mechanisms, diagnostic delays, and necessary regulatory corrections.

Sex-Specific Risks of GLP-1 Agonists: Weighing Efficacy Against Gastrointestinal Toxicity in Women

Women using semaglutide or tirzepatide achieve significant weight loss but encounter gastrointestinal adverse events at disproportionately higher frequencies than men. This post reviews evidence linking estrogen signaling to nausea sensitivity, trial versus real-world data discrepancies, and titration adjustments.

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The Female Phenotype of Heart Failure with Preserved Ejection Fraction: Diagnosis, Trials, and Treatment Gaps

Epidemiology and Diagnostic Ambiguity Heart failure with preserved ejection fraction (HFpEF) represents a rapidly growing clinical challenge, with incidence rat...

The Autonomic Divide: Biological Sex Differences and Diagnostic Delays in Postural Orthostatic Tachycardia Syndrome

The Autonomic Divide: Biological Sex Differences and Diagnostic Delays in Postural Orthostatic Tachycardia Syndrome Postural orthostatic tachycardia syndrome (P...

Beyond Aggregate Statistics: Sex-Specific Gaps in Living Kidney Donation Risk Counseling

Beyond Aggregate Statistics: Rethinking Risk Stratification in Living Kidney Donation Current clinical guidelines for living kidney donation frequently rely on...

The Survival Paradox: Sex Differences in Systemic Sclerosis and Organ Outcomes

The Epidemiological Imbalance Systemic sclerosis (SSc), widely recognized as scleroderma, represents one of the most pronounced examples of sex-biased autoimmun...